Windows Update leaves lots of files, which you don’t need anymore. The Disk Cleanup utility lets you remove those files. Unfortunately the tool needs to be “installed” on Windows Server 2008 and 2008 R2. There is a Guide over here – http://technet.microsoft.com/en-us/library/ff630161%28WS.10%29.aspx Instructions for Windows Server 2012 are within the comments of the linked article.
Every time I suspend a VM on my VMWare Workstation, there is a long running disk activity on the associated vmem file. This file is a copy of the virtual machines pagefile running on the host instead of the guest. Suspending a VM shows a progress bar, which is pretty fast. But even a long time (minutes) after it has vanished, the disk activity still continues. The setting mainMem.useNamedFile = “FALSE” will configure VMWare to use the host paging file instead of a vmem file.